ENHANCED NEUTRALIZATION ESCAPE TO THERAPEUTIC MONOCLONAL ANTIBODIES BY SARS-COV-2 OMICRON SUB-LINEAGES


FE or not FE? A Play in Two Acts

The play that follows is a highly experimental work in Cannabinoid Booster progress.It is deliberately playful, and at times absurd, which all too often reflects the lived experiences of workers in the sector.The narrative form is employed to examine the potential challenges of engagement in scholarship, particularly methodology, for lecturers in f

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Cellular and functional evaluation of LDLR missense variants reported in hypercholesterolemic patients demonstrates their hypomorphic impacts on trafficking and LDL internalization

BackgroundFamilial hypercholesterolemia (FH) is an autosomal dominant disorder characterized by increased LDL-cholesterol levels.About 85% of FH cases are caused by LDLR mutations encoding the low-density lipoprotein receptor (LDLR).LDLR is synthesized in the endoplasmic reticulum (ER) where it undergoes post-translational modifications and then tr

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